Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573085 | 0.97 | NR1H4 (0.56) | NR1H4KEAP1NFE2L2SMN1; SMN2UTS2R | |
| SCHEMBL27558113 | 0.83 | CNR2 (0.65) | KEAP1NFE2L2SMN1; SMN2UTS2RKMT2A | |
| SCHEMBL6956276 | 0.83 | CNR2 (0.65) | KEAP1NFE2L2SMN1; SMN2UTS2RKMT2A | |
| SCHEMBL28760324 | 0.83 | CNR2 (0.65) | KEAP1NFE2L2SMN1; SMN2UTS2RKMT2A | |
| SCHEMBL4956568 | 0.81 | NR1H4 (0.58) | NR1H4KMT2AMEN1NLRP3CASP1 | |
| SCHEMBL2314623 | 0.75 | PIN1 (0.59) | NR1H4SMN1; SMN2UTS2RKMT2AMEN1 | |
| SCHEMBL2315069 | 0.75 | PIN1 (0.59) | NR1H4SMN1; SMN2UTS2RKMT2AMEN1 | |
| SCHEMBL2314616 | 0.75 | PIN1 (0.59) | NR1H4SMN1; SMN2UTS2RKMT2AMEN1 | |
| SCHEMBL7359308 | 0.74 | SLC1A3 (0.50) | SMN1; SMN2UTS2RITGB3ITGA2B | |
| SCHEMBL6953151 | 0.74 | KMT2A (0.71) | KEAP1NFE2L2UTS2RKMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070243255-A1 | Multifunctional supramolecular hydrogels as biomaterials | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2007-10-18 | — | — | US | disclosed |
| US-20070224273-A1 | Multifunctional Supramolecular Hydrogels as Biomaterials | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2007-09-27 | — | — | US | disclosed |