Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613410 | 0.90 | DRD2 (0.55) | DRD2OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL613489 | 0.90 | OPRM1 (0.50) | OPRM1OPRK1OPRL1SLC6A4SLC6A3 | |
| SCHEMBL2385636 | 0.90 | OPRM1 (0.43) | DRD2OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL612754 | 0.90 | OPRM1 (0.43) | DRD2OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL742824 | 0.90 | DRD2 (0.37) | DRD2OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL612712 | 0.90 | OPRL1 (0.52) | OPRM1OPRK1OPRL1ALDH1A1POLB | |
| SCHEMBL20010952 | 0.87 | OPRL1 (0.42) | DRD2OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL12208679 | 0.87 | SLC6A4 (0.33) | DRD2OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL744629 | 0.86 | ALDH1A1 (0.34) | DRD2OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL743942 | 0.86 | OPRM1 (0.47) | DRD2OPRM1OPRK1OPRL1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447435-B1 | 1,4-Di-(trans-4-Cyclohexyl)benzene derivatives and their use in liquid crystal media and liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-10-24 | — | — | EP | disclosed |