Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400049 | 0.87 | RECQL (0.47) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14404095 | 0.80 | MAPT (0.44) | GAAMAPTMEN1KMT2AHTT | |
| SCHEMBL14404373 | 0.79 | MAPT (0.49) | GAAMAPTMEN1KMT2AHTT | |
| SCHEMBL14404093 | 0.78 | PPARG (0.42) | GAAMAPTMEN1KMT2AHTT | |
| SCHEMBL14404094 | 0.78 | GAA (0.42) | GAAMAPTMEN1KMT2AHTT | |
| SCHEMBL14404108 | 0.78 | MAPT (0.53) | GAAMAPTMEN1KMT2AHTT | |
| SCHEMBL14404175 | 0.76 | ALDH1A1 (0.56) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14400143 | 0.73 | KMT2A (0.46) | GAAMAPTMEN1KMT2AHTT | |
| SCHEMBL14399813 | 0.73 | RECQL (0.43) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14399915 | 0.72 | GAA (0.53) | GAAMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007116314-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (US) | 2007-10-18 | — | — | WO | disclosed |