Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399900 | 0.89 | RECQL (0.59) | ALDH1A1MAPTKMT2AMEN1AGTR1 | |
| SCHEMBL14404178 | 0.86 | MAPT (0.53) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL683929 | 0.86 | KDM4E (0.60) | ALDH1A1MAPTKMT2AMEN1AGTR1 | |
| SCHEMBL14404141 | 0.83 | RAB9A (0.57) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL14404174 | 0.81 | MAPT (0.54) | ALDH1A1MAPTKMT2AMEN1AGTR1 | |
| SCHEMBL14404040 | 0.80 | MAPT (0.45) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL14400032 | 0.78 | MAPT (0.57) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL9654244 | 0.78 | RECQL (0.71) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL684651 | 0.77 | KDM1A (0.65) | ALDH1A1MAPTKMT2AMEN1AGTR1 | |
| SCHEMBL14404109 | 0.76 | GAA (0.40) | ALDH1A1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007116314-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (US) | 2007-10-18 | — | — | WO | disclosed |