Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400032 | 0.92 | MAPT (0.57) | MAPTL3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL14404175 | 0.86 | ALDH1A1 (0.56) | MAPTL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14404174 | 0.85 | MAPT (0.54) | MAPTL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14399900 | 0.82 | RECQL (0.59) | MAPTL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14404040 | 0.79 | MAPT (0.45) | MAPTTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14404093 | 0.79 | PPARG (0.42) | MAPTL3MBTL1TDP1PPARGPPARA | |
| SCHEMBL14399944 | 0.78 | KDM1A (0.62) | MAPTL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10395930 | 0.77 | RECQL (0.62) | MAPTL3MBTL1PPARGPPARARAB9A | |
| SCHEMBL14404141 | 0.77 | RAB9A (0.57) | MAPTL3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL14399703 | 0.77 | TDP1 (0.56) | MAPTL3MBTL1TDP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007116314-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (US) | 2007-10-18 | — | — | WO | disclosed |