Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051060 | 0.90 | ESR1 (0.42) | ESR1ESR2MCHR1KMT2ADRD2 | |
| SCHEMBL14051122 | 0.89 | ESR1 (0.41) | ESR1ESR2KMT2ADRD2PPARA | |
| SCHEMBL14404749 | 0.87 | CYP3A4 (0.43) | ESR1ESR2MCHR1KMT2ADRD2 | |
| SCHEMBL14404649 | 0.86 | SIGMAR1 (0.41) | ESR1ESR2MCHR1KMT2APPARA | |
| SCHEMBL5108778 | 0.85 | ESR1 (0.53) | ESR1ESR2F10 | |
| SCHEMBL14051061 | 0.82 | HRH3 (0.43) | ESR1ESR2MCHR1PPARAPPARG | |
| SCHEMBL14404661 | 0.81 | CA1 (0.37) | ESR1ESR2MCHR1KMT2ADRD2 | |
| SCHEMBL14032447 | 0.80 | ESR1 (0.50) | ESR1ESR2KMT2A | |
| SCHEMBL14032413 | 0.80 | ESR1 (0.50) | ESR1ESR2KMT2A | |
| SCHEMBL5109144 | 0.79 | BCHE (0.43) | ESR1ESR2KMT2ADRD2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279489-B2 | Compounds and methods for modulation of estrogen receptors | SIGNAL PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |