Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101895 | 0.82 | TAAR1 (0.43) | LTA4HTAAR1ESR1ESR2SLC6A2 | |
| SCHEMBL11612983 | 0.82 | TSHR (0.43) | LTA4HTAAR1ESR1ESR2SLC6A2 | |
| SCHEMBL14407103 | 0.81 | ESR1 (0.37) | ESR1ESR2ALDH1A1 | |
| SCHEMBL8095627 | 0.79 | LTA4H (0.53) | LTA4HTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8087746 | 0.78 | BCL2 (0.45) | LTA4H | |
| SCHEMBL21970560 | 0.77 | SKP2 (0.50) | LTA4HTAAR1ESR1ESR2SLC6A2 | |
| SCHEMBL24895124 | 0.76 | ESR1 (0.47) | LTA4HTAAR1ESR1ESR2DAO | |
| SCHEMBL25381582 | 0.74 | CYP2A6 (0.55) | LTA4HTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2090458 | 0.73 | TAAR1 (0.56) | LTA4HTAAR1TYMPCNR2GPR55 | |
| SCHEMBL29477327 | 0.73 | TAAR1 (0.56) | LTA4HTAAR1TYMPCNR2GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2540163-A1 | Nematocide N-cyclopropyl-sulfonylamide derivatives | Bayer CropScience AG (DE) | 2013-01-02 | — | — | EP | disclosed |