Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455072 | 0.94 | CALM1 (0.50) | BCL2BCL2L1ALOX5LTA4HIDH1 | |
| SCHEMBL29675199 | 0.94 | CALM1 (0.50) | BCL2BCL2L1ALOX5LTA4HIDH1 | |
| SCHEMBL8101895 | 0.92 | TAAR1 (0.43) | LTA4H | |
| SCHEMBL2140995 | 0.87 | CALM1 (0.57) | BCL2BCL2L1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9741301 | 0.87 | CALM1 (0.55) | BCL2BCL2L1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29940610 | 0.87 | CALM1 (0.55) | BCL2BCL2L1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL275838 | 0.87 | CALM1 (0.55) | BCL2BCL2L1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8099386 | 0.85 | HTR2A (0.42) | BCL2BCL2L1ALOX5CYP3A4CYP2D6 | |
| SCHEMBL21305403 | 0.85 | ALOX5 (0.43) | BCL2BCL2L1ALOX5LTA4HIDH1 | |
| SCHEMBL8085589 | 0.85 | LTA4H (0.44) | CYP3A4CYP2D6CYP2C19TSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |