Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378299 | 0.93 | POLB (0.51) | LTA4HTAAR1KEAP1TSHRACHE | |
| SCHEMBL2140995 | 0.93 | CALM1 (0.57) | LTA4HTAAR1KEAP1TSHRHTR2A | |
| SCHEMBL29940610 | 0.92 | CALM1 (0.55) | LTA4HTAAR1TSHRACHEHTR2A | |
| SCHEMBL9741301 | 0.92 | CALM1 (0.55) | LTA4HTAAR1TSHRACHEHTR2A | |
| SCHEMBL275838 | 0.92 | CALM1 (0.55) | LTA4HTAAR1TSHRACHEHTR2A | |
| SCHEMBL27614158 | 0.90 | CALM1 (0.52) | LTA4HTAAR1TSHRACHEHTR2A | |
| Hydrochloric Acid SCHEMBL21175607 | 0.90 | CALM1 (0.52) | LTA4HTAAR1TSHRHTR2ACALM1 | |
| SCHEMBL10863097 | 0.90 | CALM1 (0.52) | LTA4HTAAR1TSHRHTR2ACALM1 | |
| SCHEMBL1584083 | 0.89 | LTA4H (0.46) | LTA4HTAAR1KEAP1TSHRACHE | |
| SCHEMBL3926343 | 0.89 | KEAP1 (0.67) | LTA4HTAAR1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |