Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503839 | 0.84 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL14409754 | 0.83 | KDM4E (0.48) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL23032664 | 0.83 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL13503591 | 0.80 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL3630848 | 0.78 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL14409764 | 0.78 | OPRM1 (0.47) | OPRM1CHRM3CHRM2 | |
| SCHEMBL26191622 | 0.73 | TAAR1 (0.37) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8331162 | 0.71 | POLB (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8807231 | 0.71 | CHRM3 (0.54) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL28891615 | 0.70 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487811-B1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2007-09-05 | — | — | EP | disclosed |