SCHEMBL14410762

SCHEMBL14410762

Cc1ccc(S(=O)(=O)OC[C@@H]2O[C@H](C)[C@H](OCc3ccccc3)C2OCc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 2/20 0.45
▸ FGF2 P09038 2/20 0.45
▸ VEGFA P15692 2/20 0.45
▸ HPSE Q9Y251 2/20 0.45
▸ CA1 P00915 2/20 0.41
▸ CA2 P00918 2/20 0.41
▸ CA9 Q16790 2/20 0.41
▸ LMNA P02545 1/20 0.38
▸ TUBB4A P04350 2/20 0.38
▸ TUBB P07437 2/20 0.38
▸ TUBA3C P0DPH7 2/20 0.38
▸ TUBA1B P68363 2/20 0.38
▸ TUBA4A P68366 2/20 0.38
▸ TUBB4B P68371 2/20 0.38
▸ TUBB3 Q13509 2/20 0.38
▸ TUBB2A Q13885 2/20 0.38
▸ TUBB8 Q3ZCM7 2/20 0.38
▸ TUBA3E Q6PEY2 2/20 0.38
▸ TUBA1A Q71U36 2/20 0.38
▸ TUBA1C Q9BQE3 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14410760 1.00 FGF1 (0.45) FGF1FGF2VEGFAHPSECA1
SCHEMBL8720284 0.89 CA1 (0.49) FGF1FGF2VEGFAHPSECA1
SCHEMBL28316892 0.88 FGF1 (0.52) FGF1FGF2VEGFAHPSECA1
SCHEMBL28315418 0.87 FGF1 (0.41) FGF1FGF2VEGFAHPSECA1
SCHEMBL20147260 0.83 FGF1 (0.40) FGF1FGF2VEGFAHPSECA1
SCHEMBL13057268 0.81 FGF1 (0.44) FGF1FGF2VEGFAHPSECA1
SCHEMBL2175355 0.81 FGF1 (0.44) FGF1FGF2VEGFAHPSECA1
SCHEMBL6929305 0.81 FGF1 (0.44) FGF1FGF2VEGFAHPSECA1
SCHEMBL6923504 0.81 FGF1 (0.44) FGF1FGF2VEGFAHPSECA1
SCHEMBL13057269 0.81 SSTR1 (0.44) FGF1FGF2VEGFAHPSECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070219144-A1 IMMUNOMODULATORY SACCHARIDE COMPOUNDS UNIVERSITY OF ALBERTA 2007-09-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219144-A1 IMMUNOMODULATORY SACCHARIDE COMPOUNDS MTX1, MTX2, CSGALNACT1 FGF1 2391/4885FGF2 2234/4885VEGFA 3817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback