Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TACR2 | P21452 | 3/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | FGF1 | P05230 | 2/20 | 0.43 |
| ▸ | FGF2 | P09038 | 2/20 | 0.43 |
| ▸ | VEGFA | P15692 | 2/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 4/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316892 | 0.90 | FGF1 (0.52) | CA1CA2CA9NT5EPTPN1 | |
| SCHEMBL28315418 | 0.89 | FGF1 (0.41) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL14410760 | 0.89 | FGF1 (0.45) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL14410762 | 0.89 | FGF1 (0.45) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL23705219 | 0.88 | CA1 (0.42) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL29384605 | 0.88 | CA1 (0.42) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL26879181 | 0.84 | CA1 (0.39) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL6923504 | 0.84 | FGF1 (0.44) | CA1CA2CA9NT5EPTPN1 | |
| SCHEMBL13057268 | 0.84 | FGF1 (0.44) | CA1CA2CA9NT5EPTPN1 | |
| SCHEMBL2175355 | 0.84 | FGF1 (0.44) | CA1CA2CA9NT5EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832898-A2 | Substituted amino acid derivatives | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |