Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446753 | 0.73 | NOS3 (0.32) | CCNA2CDK2CCNA1 | |
| SCHEMBL8626075 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL10323668 | 0.69 | CYP1A2 (0.36) | CCNA2CDK2CCNA1 | |
| SCHEMBL4716502 | 0.69 | — | — | |
| SCHEMBL2898609 | 0.69 | RAB9A (0.40) | — | |
| Hydrochloric Acid SCHEMBL10954513 | 0.68 | LMNA (0.42) | — | |
| SCHEMBL4072762 | 0.66 | — | — | |
| SCHEMBL27103191 | 0.66 | CSNK1A1 (0.46) | — | |
| SCHEMBL17677246 | 0.66 | POLB (0.39) | — | |
| SCHEMBL1168107 | 0.66 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539755-B1 | 6-ALKOXY-PYRIDO-PYRIMIDINES AS P-38 MAP KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-09-26 | — | — | EP | disclosed |