Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023082 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CES2CES1PLA2G2APLA2G5 | |
| SCHEMBL4023079 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CES2CES1PLA2G2APLA2G5 | |
| SCHEMBL22424763 | 0.77 | ALDH1A1 (0.44) | ALDH1A1PLA2G2APLA2G5AKR1B1GPR84 | |
| SCHEMBL28892954 | 0.76 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G5GPR84FFAR1 | |
| SCHEMBL28893067 | 0.76 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G5GPR84FFAR1 | |
| SCHEMBL28893146 | 0.76 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G5GPR84FFAR1 | |
| SCHEMBL1654403 | 0.76 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G5GPR84FFAR1 | |
| SCHEMBL16499600 | 0.76 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G5GPR84FFAR1 | |
| SCHEMBL28892975 | 0.76 | PLA2G2A (0.44) | ALDH1A1PLA2G2APLA2G5GPR84FFAR1 | |
| SCHEMBL22917267 | 0.75 | ALDH1A1 (0.38) | ALDH1A1CES2CES1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555260-B1 | Phenyltetrazole compounds | DIPHARMA FRANCIS SRL (IT) | 2007-09-19 | — | — | EP | disclosed |