Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TTK | P33981 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561564 | 0.79 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL730639 | 0.79 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL298966 | 0.79 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL5693192 | 0.79 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL7331545 | 0.79 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL7329986 | 0.79 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL7331167 | 0.79 | KDM4E (0.57) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL31190846 | 0.79 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL29643994 | 0.79 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL13665430 | 0.78 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643930-B2 | Substituted indazole derivatives as in vitro MAO-B inhibitors | “NTZ LAB” LTD. (BG) | 2017-05-09 | — | — | US | disclosed |
| EP-2964219-B1 | SUBSTITUTED INDAZOLE OR INDOLE DERIVATIVES AS IN VITRO MAO-B INHIBITORS | NTZ LAB LTD (BG) | 2017-05-03 | — | — | EP | disclosed |
| US-20150353504-A1 | SUBSTITUTED INDAZOLE DERIVATIVES AS IN VITRO MAO-B INHIBITORS | "NTZ LAB" LTD. (BG) | 2015-12-10 | — | — | US | disclosed |
| WO-2007100759-A2 | METHOD FOR TREATING COMMON VARIABLE IMMUNODEFICIENCY | SYNTA PHARMACEUTICALS CORP. (US) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353504-A1 | SUBSTITUTED INDAZOLE DERIVATIVES AS IN VITRO MAO-B INHIBITORS | MAOB, MAOA, HNMT | KDM4E 1359/4885GAA 73/4885PDPK1 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.