Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.60 |
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
| ▸ | VNN1 | O95497 | 6/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21763292 | 0.83 | TACR3 (0.71) | SPRTACR3CYP2C9ALDH1A1 | |
| SCHEMBL19658651 | 0.82 | SPR (0.55) | SPRVNN1CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL13873601 | 0.81 | SPR (0.54) | SPRTACR3VNN1CYP3A4CYP2D6 | |
| SCHEMBL17888400 | 0.81 | ALDH1A1 (0.62) | SPRVNN1ALDH1A1MAPTHTT | |
| SCHEMBL13873199 | 0.81 | SPR (0.54) | SPRTACR3VNN1CHRM2CHRM1 | |
| SCHEMBL23791367 | 0.81 | GPR119 (0.59) | SPRTACR3VNN1CHRM2CHRM1 | |
| SCHEMBL18714672 | 0.81 | GPR119 (0.59) | SPRTACR3VNN1CHRM2CHRM1 | |
| SCHEMBL21078119 | 0.80 | SPR (0.58) | SPRVNN1ALDH1A1 | |
| SCHEMBL16312222 | 0.79 | CHRNA7 (0.51) | SPRMAP4K4CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL19658664 | 0.79 | EPHX2 (0.56) | SPRVNN1CHRNA7CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |