Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413535 | 0.92 | EPHX2 (0.47) | MAPTKMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL4107931 | 0.88 | MAPT (0.50) | MAPTKMT2AL3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL23245656 | 0.84 | MAPT (0.46) | MAPTKMT2AL3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL21412280 | 0.84 | MAPT (0.46) | MAPTKMT2AL3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL13873155 | 0.80 | RORC (0.43) | MAPTKMT2ALMNAGAAEPHX2 | |
| SCHEMBL21426006 | 0.80 | MMP13 (0.49) | KMT2AMEN1 | |
| SCHEMBL21426005 | 0.80 | MMP13 (0.49) | KMT2AMEN1 | |
| SCHEMBL20002563 | 0.80 | EPHX2 (0.45) | MAPTKMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL20002980 | 0.79 | CYP2C19 (0.59) | MAPTKMT2AL3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL14305129 | 0.77 | SPR (0.49) | HTR2AHTR2CKCNH2LMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |