Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873301 | 0.85 | EPHX2 (0.74) | KDM4EEPHX2LIPE | |
| SCHEMBL830019 | 0.76 | KDM4E (0.62) | KDM4EEPHX2KMT2ALMNAMAPT | |
| SCHEMBL14413342 | 0.76 | SMN1; SMN2 (0.72) | EPHX2KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14413644 | 0.72 | EPHX2 (0.75) | EPHX2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21698459 | 0.72 | KMT2A (0.62) | KDM4EEPHX2KMT2ALMNAMAPT | |
| SCHEMBL14413883 | 0.71 | EPHX2 (0.74) | EPHX2KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL13873419 | 0.70 | EPHX2 (1.00) | EPHX2LIPE | |
| SCHEMBL14413584 | 0.70 | EPHX2 (0.65) | KDM4EEPHX2KMT2AMAPTALDH1A1 | |
| SCHEMBL1574956 | 0.69 | MAPT (0.66) | KMT2AMAPTGRIN2BPAX8SMN1; SMN2 | |
| SCHEMBL13873290 | 0.69 | EPHX2 (1.00) | EPHX2LMNALIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |