Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23344462 | 0.78 | LMNA (0.44) | THRBLMNAL3MBTL1TDP1 | |
| E968 SCHEMBL29094185 | 0.77 | THRB (0.65) | THRBLMNAL3MBTL1TDP1 | |
| SCHEMBL24136366 | 0.71 | TDP1 (0.36) | LMNAL3MBTL1TDP1 | |
| SCHEMBL9815505 | 0.70 | THRB (0.35) | THRB | |
| SCHEMBL5822752 | 0.70 | THRB (0.55) | THRBLMNAL3MBTL1TDP1 | |
| SCHEMBL9564560 | 0.68 | — | — | |
| SCHEMBL346604 | 0.68 | — | — | |
| SCHEMBL4409028 | 0.68 | — | — | |
| SCHEMBL4409027 | 0.68 | — | — | |
| SCHEMBL283543 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098597-A1 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2007-09-07 | — | — | WO | disclosed |