Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136468 | 0.81 | TDP1 (0.33) | TDP1LMNAL3MBTL1 | |
| SCHEMBL25856570 | 0.79 | — | — | |
| SCHEMBL283630 | 0.74 | — | — | |
| SCHEMBL60554 | 0.74 | — | — | |
| SCHEMBL1089459 | 0.74 | — | — | |
| SCHEMBL14413745 | 0.71 | THRB (0.46) | TDP1LMNAL3MBTL1 | |
| SCHEMBL23344462 | 0.70 | LMNA (0.44) | TDP1LMNAL3MBTL1 | |
| SCHEMBL16076528 | 0.69 | — | — | |
| Propane SCHEMBL2402465 | 0.69 | TDP1 (0.47) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| E968 SCHEMBL18493349 | 0.68 | TDP1 (0.77) | TDP1LMNAL3MBTL1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928967-A1 | SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2021-12-29 | — | — | EP | disclosed |