Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.62 |
| ▸ | NAMPT | P43490 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.53 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.53 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32660750 | 0.86 | TRPV1 (0.62) | TRPV1NAMPTMAPTEPHX2CNR1 | |
| SCHEMBL14393776 | 0.86 | EPHX2 (0.70) | TRPV1NAMPTMAPTEPHX2CNR1 | |
| SCHEMBL4559682 | 0.83 | MAPT (0.73) | TRPV1NAMPTMAPTEPHX2CNR1 | |
| SCHEMBL14306236 | 0.83 | MAPT (0.69) | TRPV1NAMPTMAPTEPHX2CNR1 | |
| SCHEMBL23573367 | 0.82 | EPHX2 (0.64) | TRPV1EPHX2 | |
| SCHEMBL8244866 | 0.82 | TRPV1 (0.62) | TRPV1NAMPTMAPTEPHX2CNR1 | |
| SCHEMBL4011037 | 0.82 | EPHX2 (0.79) | EPHX2 | |
| SCHEMBL6153200 | 0.82 | KMT2A (0.69) | TRPV1NAMPTMAPTEPHX2CNR1 | |
| SCHEMBL20271463 | 0.80 | TRPV1 (0.63) | TRPV1NAMPTMAPTEPHX2CNR1 | |
| SCHEMBL15134839 | 0.79 | EPHX2 (0.69) | TRPV1NAMPTMAPTEPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106706-A1 | CYCLIC UREA COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS EFFECTIVE FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |