Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.81 |
| ▸ | BCHE | P06276 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758219 | 0.77 | HTR6 (1.00) | HTR6BCHE | |
| Hydrochloric Acid SCHEMBL4084578 | 0.76 | HTR6 (0.98) | HTR6BCHE | |
| SCHEMBL5960063 | 0.76 | HTR6 (0.62) | HTR6 | |
| SCHEMBL13711071 | 0.74 | HTR6 (0.66) | HTR6BCHE | |
| SCHEMBL14415499 | 0.70 | HTR6 (0.62) | HTR6BCHE | |
| SCHEMBL17726298 | 0.68 | DRD4 (0.71) | BCHE | |
| SCHEMBL5960057 | 0.67 | PDE4A (0.52) | HTR6 | |
| SCHEMBL4916089 | 0.66 | CHRM2 (0.81) | BCHE | |
| SCHEMBL3964772 | 0.65 | MAPT (0.71) | BCHEPKM | |
| SCHEMBL30015410 | 0.65 | LMNA (0.53) | HTR6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271180-B2 | 1-Aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-09-18 | — | — | US | disclosed |