Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 9/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501681 | 0.90 | VDR (0.56) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL14495178 | 0.88 | ALDH1A1 (0.61) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL14483929 | 0.87 | VDR (0.58) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL14483898 | 0.87 | VDR (0.58) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL14483899 | 0.87 | VDR (0.58) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL6045305 | 0.86 | VDR (0.75) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL19986503 | 0.86 | VDR (0.75) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL14501677 | 0.85 | VDR (0.55) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL14415915 | 0.85 | VDR (0.55) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL14501672 | 0.85 | VDR (0.55) | VDRADRA1ANR1I2PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362287-B2 | Stereoselective synthesis of vitamin D analogues | LEO PHARMA A/S (DK) | 2013-01-29 | — | — | US | disclosed |
| US-20070215455-A1 | Isomerisation of pharmaceutical intermediates | LEO PHARMA A/S (DK) | 2007-09-20 | — | — | US | disclosed |
| US-20070027333-A1 | Stereoselective synthesis of vitamin d analogues | LEO PHARMA A/S (DK) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027333-A1 | Stereoselective synthesis of vitamin d analogues | CYP24A1, CYP2R1, VDR | VDR 3/4885ADRA1A 3260/4885NR1I2 2529/4885 |
| US-20070215455-A1 | Isomerisation of pharmaceutical intermediates | CYP24A1, CYP2R1, VDR | VDR 3/4885ADRA1A 1233/4885NR1I2 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.