SCHEMBL14416004

SCHEMBL14416004

CC(C)c1cn(CCCN)cn1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 17/20 0.51
CPB1 P15086 10/20 0.51
CPA1 P15085 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
MTOR P42345 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23376691 0.89 CPB2 (0.47) CPB2CPB1CPA1CYP2C9TSHR
SCHEMBL24501919 0.84 CPB2 (0.46) CPB2CPB1CPA1
SCHEMBL26038341 0.82 CPB2 (0.42) CPB2CPB1CPA1
SCHEMBL24501675 0.81 TBXAS1 (0.43) CPB2CPB1
SCHEMBL12710071 0.79 KDM5A (0.39) CPB2CPB1CPA1
SCHEMBL24496372 0.79 CPB2 (0.40) CPB2CPB1CPA1CYP2C9TSHR
SCHEMBL20968162 0.79 CPB2 (0.49) CPB2CPB1
SCHEMBL24495990 0.78 CPB2 (0.40) CPB2CPB1CPA1
SCHEMBL24496206 0.78 CPB2 (0.38) CPB2CPB1CPA1
SCHEMBL25581832 0.78 CPB2 (0.54) CPB2CPB1CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070213340-A1 Farnesyl protein transferase inhibitors SCHERING CORPORATION 2007-09-13 US disclosed
US-20070213340-A1 Farnesyl protein transferase inhibitors SCHERING CORPORATION 2007-09-13 US disclosed
WO-2007084498-A1 PIPERAZINE DERIVATIVES AS FARNESYL PROTEIN TRANSFERASE INHIBITORS SCHERING CORPORATION (US) 2007-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213340-A1 Farnesyl protein transferase inhibitors FNTB, FNTA, FDPS CPB2 1355/4885CPB1 708/4885CPA1 2510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.