Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | HAT1 | O14929 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 3/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1569897 | 0.85 | HCAR3 (0.60) | HCAR3ALDH1A1KDM4ETLR7HAT1 | |
| SCHEMBL12953802 | 0.85 | HCAR3 (0.56) | HCAR3ALDH1A1KDM4ETLR7HAT1 | |
| SCHEMBL1569893 | 0.85 | HCAR3 (0.60) | HCAR3ALDH1A1KDM4ETLR7HAT1 | |
| SCHEMBL13304709 | 0.84 | HCAR3 (0.55) | HCAR3ALDH1A1KDM4ETLR7HAT1 | |
| SCHEMBL10026856 | 0.83 | HCAR3 (0.54) | HCAR3ALDH1A1KDM4ETLR7HAT1 | |
| SCHEMBL21274635 | 0.83 | HCAR3 (0.54) | HCAR3ALDH1A1KDM4ETLR7HAT1 | |
| SCHEMBL12327198 | 0.82 | HCAR3 (0.56) | HCAR3ALDH1A1KDM4EFYNDEGS1 | |
| SCHEMBL21274631 | 0.81 | HCAR3 (0.52) | HCAR3ALDH1A1KDM4ETLR7HAT1 | |
| SCHEMBL13662111 | 0.80 | RAB9A (0.50) | HCAR3ALDH1A1KDM4EHSD17B10USP2 | |
| SCHEMBL827800 | 0.79 | HCAR3 (0.60) | HCAR3ALDH1A1KDM4EFYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136431-B | Pyridone and pyrimidone derivatives as plasma thromboplastin antecedent a inhibitor | 小野药品工业株式会社 | 2017-03-15 | — | — | CN | disclosed |
| US-7271270-B2 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-09-18 | — | — | US | disclosed |