Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 13/20 | 0.49 |
| ▸ | AXL | P30530 | 3/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL639634 | 1.00 | PRKCI (0.49) | PRKCIAXLPLK4PRKCZITK | |
| SCHEMBL639635 | 1.00 | PRKCI (0.49) | PRKCIAXLPLK4PRKCZITK | |
| SCHEMBL661039 | 0.89 | PRKCZ (0.55) | PRKCIPRKCZITK | |
| SCHEMBL3960929 | 0.89 | HRH3 (0.47) | PLK4PRKCZITK | |
| Hydrochloric Acid SCHEMBL30958672 | 0.87 | HRH3 (0.46) | PLK4PRKCZITK | |
| Trifluoroacetic Acid SCHEMBL26600062 | 0.85 | HRH4 (0.53) | PRKCI | |
| SCHEMBL17961734 | 0.81 | KDM1A (0.51) | AXL | |
| SCHEMBL2343007 | 0.81 | KDM1A (0.51) | AXL | |
| SCHEMBL4932040 | 0.80 | PRKCI (0.46) | PRKCIAXLPRKCZ | |
| SCHEMBL23012617 | 0.80 | CHRNB2 (0.48) | PRKCIAXLPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219191-A1 | 3-Pyridinium Methyl Cephem Compound | SHIONOGI & CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219191-A1 | 3-Pyridinium Methyl Cephem Compound | ABL1, CRKL, MGMT | PRKCI 4431/4885AXL 1467/4885PLK4 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.