Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1889602 | 0.95 | IDO1 (0.65) | IDO1BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL14417358 | 0.88 | ALOX5 (0.61) | IDO1BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL1894082 | 0.87 | IDO1 (0.54) | IDO1BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL22073078 | 0.86 | IDO1 (0.59) | IDO1ALOX5BCL2L1HSD17B1HSD17B2 | |
| SCHEMBL19939380 | 0.86 | ADORA2A (0.49) | IDO1BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL11064751 | 0.84 | HPGD (0.65) | IDO1BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL14417379 | 0.83 | COMT (0.62) | IDO1BACE1MEN1KMT2ALMNA | |
| SCHEMBL30663218 | 0.82 | IDO1 (0.48) | IDO1BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL20565615 | 0.82 | IDO1 (0.48) | IDO1BACE1ALOX5ALDH1A1HPGD | |
| SCHEMBL1890061 | 0.81 | MCL1 (0.58) | IDO1ALDH1A1HPGDHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070212569-A1 | ORGANOMETALLIC COMPLEX FOR ORGANIC LIGHT-EMITTING LAYER AND ORGANIC LIGHT-EMITTING DIODE USING THE SAME | SFC CO., LTD. (KR) | 2007-09-13 | — | — | US | disclosed |