SCHEMBL1894082

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1894222	0.90	HPGD (0.50)	IDO1ALOX5BACE1ALDH1A1HPGD
	SCHEMBL14417401	0.87	IDO1 (0.59)	IDO1ALOX5BACE1ALDH1A1HPGD
	SCHEMBL1889602	0.87	IDO1 (0.65)	IDO1ALOX5BACE1ALDH1A1HPGD
	SCHEMBL14417358	0.80	ALOX5 (0.61)	IDO1ALOX5BACE1ALDH1A1HPGD
	SCHEMBL21131727	0.78	ADORA2A (0.45)	IDO1ALOX5BACE1ALDH1A1HPGD
	SCHEMBL14417222	0.78	IDO1 (0.52)	IDO1ALOX5LMNAHTTESR2
	SCHEMBL13265824	0.77	IDO1 (0.81)	IDO1ALDH1A1HPGDHSD17B10KDM4E
	SCHEMBL442916	0.77	IDO1 (0.81)	IDO1ALDH1A1HPGDHSD17B10KDM4E
	SCHEMBL24637791	0.76	HPGD (0.73)	ALOX5BACE1ALDH1A1HPGDHSD17B10
	SCHEMBL11064751	0.76	HPGD (0.65)	IDO1ALOX5BACE1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.