Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.65 |
| ▸ | CDK4 | P11802 | 2/20 | 0.57 |
| ▸ | CCND1 | P24385 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1889602 | 0.88 | IDO1 (0.65) | HPGDHSD17B10ALDH1A1BCL2L1CDK4 | |
| SCHEMBL1894222 | 0.87 | HPGD (0.50) | HPGDHSD17B10ALDH1A1BCL2L1CDK4 | |
| SCHEMBL2391683 | 0.84 | ALDH1A1 (0.52) | HPGDHSD17B10ALDH1A1BCL2L1BACE1 | |
| SCHEMBL14417401 | 0.84 | IDO1 (0.59) | HPGDHSD17B10ALDH1A1BCL2L1CDK4 | |
| SCHEMBL28735041 | 0.82 | ALDH1A1 (0.54) | HPGDHSD17B10ALDH1A1BCL2L1CDK4 | |
| SCHEMBL8481452 | 0.79 | HPGD (0.89) | HPGDHSD17B10ALDH1A1BCL2L1BACE1 | |
| 2-Phenylphenol SCHEMBL14249267 | 0.79 | ALDH1A1 (1.00) | HPGDHSD17B10ALDH1A1BCL2L1BACE1 | |
| 2-Phenylphenol SCHEMBL29360750 | 0.79 | ALDH1A1 (1.00) | HPGDHSD17B10ALDH1A1BCL2L1BACE1 | |
| SCHEMBL30080985 | 0.79 | METAP2 (0.48) | HPGDHSD17B10ALDH1A1BCL2L1CDK4 | |
| SCHEMBL28366972 | 0.79 | ALDH1A1 (1.00) | HPGDHSD17B10ALDH1A1BCL2L1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448869-A | HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-15 | — | — | US | claimed |