Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 5/20 | 0.76 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.76 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.69 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | CES2 | O00748 | 1/20 | 0.69 |
| ▸ | APAF1 | O14727 | 1/20 | 0.69 |
| ▸ | TERT | O14746 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | CES1 | P23141 | 1/20 | 0.69 |
| ▸ | APEX1 | P27695 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16152283 | 1.00 | EED (0.76) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Tanshinone Iib SCHEMBL11945767 | 0.86 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Tanshinone Iib SCHEMBL14417728 | 0.86 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL16152326 | 0.85 | EED (0.78) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Tanshinone Iia SCHEMBL2026738 | 0.82 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Isotanshinone Iib SCHEMBL30381469 | 0.79 | EED (0.85) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Methyl Tanshinonate SCHEMBL16152293 | 0.78 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Methyl Tanshinonate SCHEMBL14417730 | 0.78 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL17663613 | 0.78 | EED (0.77) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Przewaquinone A SCHEMBL16152272 | 0.76 | IDO1 (1.00) | EEDSUZ12EZH2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070207989-A1 | DITERPENE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR, CANCER AND INFLAMMATORY DISEASES | SAVIPU PHARMACEUTICALS (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207989-A1 | DITERPENE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR, CANCER AND INFLAMMATORY DISEASES | NFKBIA, EDNRA, EDNRB | EED 2840/4885SUZ12 1953/4885EZH2 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.