Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 5/20 | 0.77 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.77 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | CES2 | O00748 | 1/20 | 0.70 |
| ▸ | APAF1 | O14727 | 1/20 | 0.70 |
| ▸ | TERT | O14746 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | CES1 | P23141 | 1/20 | 0.70 |
| ▸ | APEX1 | P27695 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tanshinone Iib SCHEMBL11945767 | 0.87 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Tanshinone Iib SCHEMBL14417728 | 0.87 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Tanshinone Iia SCHEMBL2026738 | 0.83 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL16152326 | 0.81 | EED (0.78) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Methyl Tanshinonate SCHEMBL14417730 | 0.80 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Methyl Tanshinonate SCHEMBL16152293 | 0.80 | EED (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Isotanshinone Iib SCHEMBL30381469 | 0.79 | EED (0.85) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL14417696 | 0.78 | EED (0.76) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL16152283 | 0.78 | EED (0.76) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL29538928 | 0.75 | EED (0.84) | EEDSUZ12EZH2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016050208-A1 | BIO-RELATED SUBSTANCE MODIFIED BY MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE | 厦门赛诺邦格生物科技有限公司 | 2016-04-07 | — | — | WO | disclosed |