⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273093 | 0.74 | — | — | |
| SCHEMBL1441833 | 0.65 | — | — | |
| SCHEMBL79661 | 0.61 | ALDH1A1 (0.39) | — | |
| SCHEMBL35663 | 0.61 | ALDH1A1 (0.39) | — | |
| SCHEMBL9275790 | 0.61 | — | — | |
| Methyl Alcohol SCHEMBL2866912 | 0.60 | ALDH1A1 (0.33) | — | |
| Hydrogen Peroxide SCHEMBL135349 | 0.60 | ALDH1A1 (0.33) | — | |
| Hydrogen Peroxide SCHEMBL135351 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL991455 | 0.59 | — | — | |
| SCHEMBL3751552 | 0.58 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045520-B2 | Synthesis of purine nucleosides | GILEAD PHARMASSET LLC (US) | 2015-06-02 | — | — | US | disclosed |
| EP-2313422-B1 | NUCLEOSIDE CYCLICPHOSPHATES | GILEAD PHARMASSET LLC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8759510-B2 | Nucleoside cyclicphosphates | GILEAD PHARMASSET LLC (US) | 2014-06-24 | — | — | US | disclosed |
| US-8716263-B2 | Synthesis of purine nucleosides | GILEAD PHARMASSET LLC (US) | 2014-05-06 | — | — | US | disclosed |
| EP-2671888-A1 | 3',5'-cyclic nucleoside phosphate analogues | Gilead Pharmasset LLC (US) | 2013-12-11 | — | — | EP | disclosed |
| US-20120316327-A1 | SYNTHESIS OF PURINE NUCLEOSIDES | GILEAD PHARMASSET LLC (US) | 2012-12-13 | — | — | US | disclosed |
| US-20120258928-A1 | NUCLEOSIDE CYCLICPHOSPHATES | GILEAD PHARMASSET LLC (US) | 2012-10-11 | — | — | US | disclosed |
| US-8173621-B2 | Nucleoside cyclicphosphates | GILEAD PHARMASSET LLC (US) | 2012-05-08 | — | — | US | disclosed |
| EP-2313422-A2 | NUCLEOSIDE CYCLICPHOSPHATES | Pharmasset, Inc. (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20100279973-A1 | SYNTHESIS OF PURINE NUCLEOSIDES | PHARMASSET, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100081628-A1 | NUCLEOSIDE CYCLICPHOSPHATES | PHARMASSET, INC. (US) | 2010-04-01 | — | — | US | disclosed |
| WO-2009152095-A2 | NUCLEOSIDE CYCLICPHOSPHATES | PHARMASSET, INC. (US) | 2009-12-17 | — | — | WO | disclosed |