Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 8/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12121844 | 1.00 | CCR1 (0.51) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL652677 | 0.90 | DRD2 (0.54) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL7205645 | 0.85 | CCR1 (0.61) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL7205649 | 0.85 | CCR1 (0.61) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL10287875 | 0.85 | DRD2 (0.50) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL12121941 | 0.84 | OPRM1 (0.48) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL13824477 | 0.82 | CCR1 (0.66) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL14419959 | 0.82 | CCR1 (0.66) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL7206934 | 0.80 | CCR1 (0.64) | CCR1DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL7206932 | 0.80 | CCR1 (0.64) | CCR1DRD2OPRM1OPRL1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271176-B2 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-09-18 | — | — | US | disclosed |