Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | BCL6 | P41182 | 2/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533521 | 0.95 | RAB9A (0.58) | RAB9AMAPTSMN1; SMN2BCL6KMT2A | |
| SCHEMBL14537505 | 0.87 | MAPT (0.51) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL4829545 | 0.85 | MAPT (0.60) | RAB9AMAPTSMN1; SMN2GAABCL6 | |
| SCHEMBL14421446 | 0.85 | CTSS (0.48) | RAB9AMAPTSMN1; SMN2BCL6KMT2A | |
| SCHEMBL14537238 | 0.85 | SMN1; SMN2 (0.57) | RAB9AMAPTSMN1; SMN2GAABCL6 | |
| SCHEMBL14533513 | 0.84 | CTSS (0.50) | RAB9AMAPTSMN1; SMN2BCL6KMT2A | |
| SCHEMBL14635367 | 0.83 | CTSS (0.45) | RAB9AMAPTSMN1; SMN2BCL6ULK1 | |
| SCHEMBL14613060 | 0.83 | CTSS (0.50) | RAB9AMAPTSMN1; SMN2BCL6KMT2A | |
| SCHEMBL4832399 | 0.83 | RAB9A (0.53) | RAB9AMAPTSMN1; SMN2GAABCL6 | |
| SCHEMBL14472384 | 0.81 | SMN1; SMN2 (0.48) | RAB9AMAPTSMN1; SMN2GAABCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265114-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7169785-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169784-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |