Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BCL6 | P41182 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GALR1 | P47211 | 4/20 | 0.42 |
| ▸ | GALR2 | O43603 | 3/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14421446 | 0.88 | CTSS (0.48) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL14537238 | 0.88 | SMN1; SMN2 (0.57) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL14533513 | 0.87 | CTSS (0.50) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL14533521 | 0.87 | RAB9A (0.58) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL14635155 | 0.87 | GALR1 (0.45) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL5550961 | 0.86 | BCL6 (0.58) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL5556198 | 0.86 | GALR1 (0.53) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL14613060 | 0.86 | CTSS (0.50) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL14472384 | 0.83 | SMN1; SMN2 (0.48) | CTSSCTSKCTSLSMN1; SMN2MAPT | |
| SCHEMBL14421535 | 0.83 | RAB9A (0.50) | CTSSCTSKCTSLSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169784-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |