Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935233 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL14422985 | 0.87 | ALDH1A1 (0.66) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL5607923 | 0.87 | ALDH1A1 (0.66) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL25095198 | 0.84 | LMNA (0.63) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL4927379 | 0.79 | FFAR1 (0.56) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL4927385 | 0.79 | FFAR1 (0.56) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL2691033 | 0.78 | HDAC1 (0.74) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL4932964 | 0.77 | NPC1 (0.58) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL4932973 | 0.77 | NPC1 (0.58) | ALDH1A1HDAC1HPGDMAPTLMNA | |
| SCHEMBL31689516 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HDAC1HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | KUREHA CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1707560-A1 | HYDROXAMIC ACID DERIVATIVE AND AGE GENERATION INHIBITOR CONTAINING THE DERIVATIVE | Kureha Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | HDAC5, HDAC1, HDAC9 | ALDH1A1 1829/4885HDAC1 2/4885HPGD 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.