Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272801 | 0.85 | CA1 (0.50) | CA1CA2CLK4ROCK1ALDH1A1 | |
| SCHEMBL210701 | 0.82 | CLK4 (0.50) | CA1CA2CLK4ROCK1ALDH1A1 | |
| SCHEMBL14424237 | 0.79 | CA1 (0.49) | CA1CA2ALDH1A1PKMDRD2 | |
| SCHEMBL209824 | 0.75 | CLK4 (0.74) | CLK4ALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL210753 | 0.75 | ALDH1A1 (0.53) | CA1CA2CLK4ROCK1ALDH1A1 | |
| SCHEMBL10272800 | 0.75 | CA1 (0.51) | CA1CA2ALDH1A1PKMDRD2 | |
| SCHEMBL15761765 | 0.75 | CXCR4 (0.66) | CA1CA2ALDH1A1PKMTSHR | |
| SCHEMBL19617458 | 0.74 | HDAC6 (0.70) | CA1CA2MAPK1DRD2TBXA2R | |
| SCHEMBL31724971 | 0.74 | HDAC6 (0.70) | CA1CA2MAPK1DRD2TBXA2R | |
| SCHEMBL1064735 | 0.74 | CA1 (0.60) | CA1CA2ALDH1A1PKMLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | METHYLGENE INC. (CA) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | HDAC1, HDAC11, HDAC5 | CA1 2297/4885CA2 1511/4885CLK4 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.