Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14425210 | 0.81 | RARG (0.61) | RXRARARARARBRARG | |
| SCHEMBL14425241 | 0.80 | CYP26B1 (0.53) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL14425245 | 0.79 | RARG (0.58) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL14425213 | 0.78 | TSHR (0.44) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL14425250 | 0.75 | RARG (0.48) | RXRARARARARBRARG | |
| SCHEMBL9208986 | 0.72 | RXRA (0.78) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL14425252 | 0.72 | RARG (0.57) | RXRARARARARBRARG | |
| SCHEMBL2897524 | 0.72 | CYP26B1 (0.53) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL16998630 | 0.71 | CYP26B1 (0.51) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL4365965 | 0.71 | CYP26B1 (0.55) | CYP26B1CYP26A1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |