Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.51 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.44 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897524 | 0.83 | CYP26B1 (0.53) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL11240978 | 0.81 | CYP26B1 (0.51) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL4365965 | 0.81 | CYP26B1 (0.55) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL6909472 | 0.80 | CYP26B1 (0.50) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL15614968 | 0.79 | KDM4E (0.40) | TAAR1KDM4EATMCYP3A4PNMT | |
| SCHEMBL4668411 | 0.79 | CYP26B1 (0.52) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL7142134 | 0.79 | CYP26B1 (0.49) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL3176733 | 0.79 | RXRA (0.54) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL8795908 | 0.77 | CYP26B1 (0.51) | CYP26B1CYP26A1RXRARXRBRXRG | |
| SCHEMBL15614940 | 0.77 | TAAR1 (0.41) | TAAR1KDM4EATMCYP3A4PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170170413-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-06-15 | — | — | US | disclosed |
| US-20170170413-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-06-15 | — | — | US | disclosed |
| WO-2015117718-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170170413-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | CYP26B1 4528/4885CYP26A1 4110/4885RXRA 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.