Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208082 | 0.82 | ALDH1A1 (0.49) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL13235630 | 0.79 | CYP3A4 (0.46) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL12248741 | 0.77 | CYP3A4 (0.60) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL2029772 | 0.77 | CYP3A4 (0.78) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL4743848 | 0.77 | CYP3A4 (0.66) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL141925 | 0.75 | CYP2C9 (0.65) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL23327143 | 0.75 | MAPK1 (0.53) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL23327352 | 0.75 | CYP3A4 (0.53) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL5209995 | 0.75 | CYP3A4 (0.53) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A | |
| SCHEMBL23327273 | 0.75 | CYP3A4 (0.53) | CYP3A4SMN1; SMN2MAPK1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185094-A1 | Novel 3-substitued-1,4-benzodiazepines | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
| US-20070185094-A1 | Novel 3-substitued-1,4-benzodiazepines | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185094-A1 | Novel 3-substitued-1,4-benzodiazepines | CCKBR, CCKAR, GABRB1 | CYP3A4 393/4885SMN1; SMN2 2931/4885MAPK1 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.