Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415954 | 0.87 | CCKAR (0.48) | CCKARTP53HTR2BPDE4DNPSR1 | |
| SCHEMBL5417682 | 0.81 | OPRK1 (0.65) | CCKARTP53HTR2BPDE4DNPSR1 | |
| SCHEMBL1574368 | 0.80 | CCKAR (0.84) | CCKARCCKBR | |
| SCHEMBL1574365 | 0.80 | CCKAR (0.84) | CCKARCCKBR | |
| SCHEMBL1574249 | 0.78 | CCKAR (0.68) | CCKARCCKBR | |
| SCHEMBL1574247 | 0.78 | CCKAR (0.68) | CCKARCCKBR | |
| SCHEMBL8667987 | 0.75 | HTR2B (0.51) | CCKARTP53HTR2BPDE4DNPSR1 | |
| SCHEMBL25411419 | 0.74 | CCKBR (0.56) | TP53HTR2BPDE4DNPSR1ALDH1A1 | |
| SCHEMBL6940247 | 0.74 | NPSR1 (0.68) | TP53NPSR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL25411426 | 0.74 | CCKBR (0.56) | TP53HTR2BPDE4DNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185094-A1 | Novel 3-substitued-1,4-benzodiazepines | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
| US-20070185094-A1 | Novel 3-substitued-1,4-benzodiazepines | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185094-A1 | Novel 3-substitued-1,4-benzodiazepines | CCKBR, CCKAR, GABRB1 | CCKAR 2/4885TP53 4751/4885HTR2B 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.