SCHEMBL14428239

SCHEMBL14428239

CC(=O)Oc1ccccc1C(=O)Nc1cc(-c2ccccc2)ccc1C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 3/20 0.46
HPGD P15428 2/20 0.46
ESR1 P03372 1/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
HMGB1 P09429 1/20 0.46
TSHR P16473 1/20 0.46
GGT1 P19440 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
BLM P54132 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HDAC1 Q13547 2/20 0.44
CFD P00746 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12165985 0.93 CFD (0.50) KDM4EALDH1A1HDAC1CFDMEN1
SCHEMBL12166039 0.89 MAPT (0.50) KDM4EALDH1A1HPGDTDP1HDAC1
SCHEMBL12166011 0.88 ACLY (0.48) KDM4EMEN1KMT2AMAPTACLY
SCHEMBL12166104 0.88 CFD (0.42) KDM4EALDH1A1HDAC1CFDMEN1
SCHEMBL12369705 0.87 KDM4E (0.56) KDM4EALDH1A1HSD17B10HPGDESR1
SCHEMBL14428481 0.83 PTGS2 (0.44) KDM4EALDH1A1HSD17B10HPGDESR1
SCHEMBL2271130 0.81 HSD17B10 (0.43) KDM4EALDH1A1HSD17B10HPGDESR1
SCHEMBL14429560 0.80 HTT (0.55) KDM4EALDH1A1HDAC1L3MBTL1MAPT
SCHEMBL13205894 0.80 CFD (0.61) KDM4EALDH1A1HSD17B10HPGDESR1
SCHEMBL1200627 0.79 MAPT (0.51) KDM4EALDH1A1HSD17B10HPGDESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed