Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14428353 | 0.86 | KCNH3 (0.47) | IDO1ACHE | |
| SCHEMBL14428372 | 0.85 | BCHE (0.38) | NPY1RNPY5RIDO1ACHE | |
| SCHEMBL6676039 | 0.83 | RAD52 (0.48) | IDO1 | |
| SCHEMBL6679140 | 0.81 | IDO1 (0.38) | IDO1ACHE | |
| SCHEMBL6679500 | 0.81 | KCNH3 (0.36) | NPY1RNPY5RIDO1ACHE | |
| SCHEMBL6365368 | 0.80 | POLB (0.49) | — | |
| SCHEMBL6673718 | 0.80 | IDO1 (0.40) | IDO1ACHE | |
| SCHEMBL6675510 | 0.80 | RAD52 (0.51) | — | |
| SCHEMBL5456625 | 0.78 | IDO1 (0.48) | IDO1ACHE | |
| SCHEMBL5450923 | 0.77 | IDO1 (0.46) | IDO1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191372-A1 | Dna-targeted benzotriazine 1,4-dioxides and their use in cancer therapy | AUCKLAND UNISERVICES LIMITED (NZ) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191372-A1 | Dna-targeted benzotriazine 1,4-dioxides and their use in cancer therapy | HIF1AN, HIF1A, HYOU1 | NPY1R 1947/4885NPY5R 1981/4885IDO1 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.