Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | CASP6 | P55212 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365368 | 0.83 | POLB (0.49) | CASP6MEN1POLBMMP14BLM | |
| SCHEMBL6678946 | 0.82 | NCF1 (0.44) | POLBKMT2ANPC1PABPC1SLC2A1 | |
| SCHEMBL6679158 | 0.82 | KCNH3 (0.48) | IDO1POLBKDM4EALDH1A1HPGD | |
| Diethylamine SCHEMBL6366261 | 0.81 | APP (0.45) | IDO1BCHEACHEAPPCASP6 | |
| SCHEMBL14428353 | 0.81 | KCNH3 (0.47) | IDO1BCHEACHEAPPCASP6 | |
| SCHEMBL14428355 | 0.81 | NPY1R (0.44) | IDO1ACHE | |
| SCHEMBL6676039 | 0.81 | RAD52 (0.48) | IDO1CASP6MEN1POLBMMP14 | |
| SCHEMBL6679187 | 0.81 | IDO1 (0.37) | IDO1BCHEACHEAPPCASP6 | |
| SCHEMBL6675510 | 0.80 | RAD52 (0.51) | POLBKMT2ANPC1SLC2A1ALDH1A1 | |
| SCHEMBL6673522 | 0.79 | ALDH1A1 (0.36) | IDO1BCHEACHEAPPCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468688-A2 | Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments | Auckland Uniservices Limited (NZ) | 2004-10-20 | — | — | EP | disclosed |