Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.42 |
| ▸ | PDE4A | P27815 | 6/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16527140 | 0.77 | RARG (0.50) | HPGDSMN1; SMN2L3MBTL1HSD17B3GAA | |
| Hydrochloric Acid SCHEMBL353933 | 0.74 | SLC6A3 (0.47) | HPGDSMN1; SMN2GAARAB9AMAPT | |
| SCHEMBL29153730 | 0.70 | HSD17B3 (0.57) | HPGDSMN1; SMN2L3MBTL1HSD17B3RAB9A | |
| SCHEMBL26254861 | 0.70 | HSD17B3 (0.82) | HPGDSMN1; SMN2L3MBTL1HSD17B3GAA | |
| SCHEMBL13408604 | 0.70 | HPGD (0.44) | HPGDSMN1; SMN2L3MBTL1HSD17B3GAA | |
| SCHEMBL26958041 | 0.69 | HSD17B3 (0.61) | HPGDSMN1; SMN2L3MBTL1HSD17B3RAB9A | |
| SCHEMBL5565698 | 0.66 | HSD17B3 (0.57) | HPGDSMN1; SMN2L3MBTL1HSD17B3GAA | |
| SCHEMBL5681582 | 0.66 | HSD17B3 (0.62) | HPGDSMN1; SMN2L3MBTL1HSD17B3GAA | |
| SCHEMBL5929944 | 0.66 | SMN1; SMN2 (0.71) | HPGDSMN1; SMN2L3MBTL1HSD17B3RAB9A | |
| SCHEMBL827814 | 0.66 | ALDH1A1 (0.60) | HPGDSMN1; SMN2HSD17B3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | CHRM3, CHRM2, CHRM5 | HPGD 863/4885SMN1; SMN2 4534/4885L3MBTL1 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.