Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 6/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599900 | 0.79 | FGFR1 (0.43) | FGFR1ASAH1MKNK1MKNK2CYP2C9 | |
| SCHEMBL14428842 | 0.77 | SLC22A12 (0.46) | MKNK2 | |
| SCHEMBL4910691 | 0.76 | FGFR1 (0.43) | FGFR1ASAH1CYP2C9IDO1KCNH2 | |
| SCHEMBL30622656 | 0.75 | FGFR1 (0.51) | FGFR1ASAH1MKNK1MKNK2LTA4H | |
| SCHEMBL5030414 | 0.73 | FGFR1 (0.46) | FGFR1ASAH1MKNK1MKNK2CYP2C9 | |
| SCHEMBL29795658 | 0.69 | ASAH1 (0.63) | FGFR1ASAH1CYP2C9TRPA1NPC1 | |
| SCHEMBL31229358 | 0.69 | KMT2A (0.55) | FGFR1ASAH1LTA4HNPC1ALDH1A1 | |
| SCHEMBL27582500 | 0.67 | LTA4H (0.35) | FGFR1ASAH1CYP2C9IDO1KCNH2 | |
| SCHEMBL10640921 | 0.67 | LTA4H (0.44) | LTA4HALDH1A1MAPTHPGD | |
| SCHEMBL15156816 | 0.65 | FGFR1 (0.47) | FGFR1CYP2C9LTA4HNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191420-A1 | Kinase inhibitors | DEVGEN NV | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191420-A1 | Kinase inhibitors | ROCK1, ROCK2, MAP3K20 | FGFR1 793/4885ASAH1 1357/4885MKNK1 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.