Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.57 |
| ▸ | PDE2A | O00408 | 2/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | AHCY | P23526 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429165 | 0.90 | PDE2A (0.55) | TYMPPDE2ASLC29A1BCHESTAT6 | |
| SCHEMBL14429061 | 0.89 | PDE2A (0.55) | TYMPPDE2ASLC29A1BCHESTAT6 | |
| SCHEMBL14429257 | 0.89 | PDE2A (0.59) | PDE2ASLC29A1STAT6ADORA2AADORA1 | |
| SCHEMBL14428965 | 0.89 | PDE2A (0.59) | PDE2ASLC29A1STAT6ADORA2AADORA1 | |
| SCHEMBL14429060 | 0.87 | P2RX3 (0.52) | TYMPPDE2ASLC29A1BCHEHTR1A | |
| SCHEMBL14428973 | 0.83 | ADK (0.51) | PDE2ASLC29A1BCHEHTR1ATP53 | |
| SCHEMBL14429255 | 0.82 | PDE2A (0.49) | TYMPPDE2ASLC29A1BCHEHTR1A | |
| SCHEMBL14429069 | 0.82 | PDE2A (0.49) | TYMPPDE2ASLC29A1BCHEHTR1A | |
| SCHEMBL14429254 | 0.82 | PDE2A (0.49) | TYMPPDE2ASLC29A1BCHEHTR1A | |
| SCHEMBL14429229 | 0.82 | PDE2A (0.49) | TYMPPDE2ASLC29A1BCHEHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | TYMP 148/4885PDE2A 3198/4885SLC29A1 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.