Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.59 |
| ▸ | AHCY | P23526 | 2/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.54 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429257 | 1.00 | PDE2A (0.59) | PDE2AAHCYADORA1HSPA5DOT1L | |
| SCHEMBL11427985 | 0.92 | PDE2A (0.64) | PDE2AAHCYADORA1HSPA5DOT1L | |
| SCHEMBL5961364 | 0.92 | PDE2A (0.64) | PDE2AAHCYADORA1HSPA5DOT1L | |
| SCHEMBL14429059 | 0.89 | TYMP (0.57) | PDE2AAHCYADORA1SLC29A1ADORA3 | |
| SCHEMBL14429057 | 0.89 | PDE2A (0.59) | PDE2AAHCYADORA1HSPA5DOT1L | |
| SCHEMBL14429024 | 0.89 | PDE2A (0.71) | PDE2AAHCYADORA1HSPA5DOT1L | |
| SCHEMBL622588 | 0.89 | ADORA1 (0.69) | PDE2AAHCYADORA1HSPA5DOT1L | |
| SCHEMBL10431915 | 0.87 | AHCY (0.62) | PDE2AAHCYADORA1HSPA5DOT1L | |
| SCHEMBL7906337 | 0.85 | HSPA5 (0.62) | PDE2AAHCYADORA1HSPA5DOT1L | |
| SCHEMBL22458248 | 0.84 | ADORA1 (0.65) | AHCYADORA1HSPA5DOT1LSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | PDE2A 3198/4885AHCY 531/4885ADORA1 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.