Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | ABL1 | P00519 | 1/20 | 0.65 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.65 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.54 |
| ▸ | NT5E | P21589 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | HK2 | P52789 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14568644 | 1.00 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14429249 | 1.00 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14568629 | 1.00 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL28795634 | 0.93 | POLB (0.76) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL264065 | 0.93 | POLB (0.76) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL264066 | 0.93 | POLB (0.76) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14733368 | 0.93 | POLB (0.76) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL9706035 | 0.93 | POLB (0.68) | POLBABL1RIN1P2RY6P2RY14 | |
| Phosphoric Acid SCHEMBL23748501 | 0.90 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL6524192 | 0.89 | POLB (0.70) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
| WO-2007025043-A2 | SEVEN-MEMBERED RING NUCLEOSIDES | IDENIX PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | POLB 368/4885ABL1 1717/4885RIN1 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.