Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | ABL1 | P00519 | 1/20 | 0.68 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.68 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.52 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.52 |
| ▸ | NT5E | P21589 | 2/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 5/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.42 |
| ▸ | DUT | P33316 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264065 | 1.00 | POLB (0.76) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14733368 | 1.00 | POLB (0.76) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL28795634 | 1.00 | POLB (0.76) | POLBABL1RIN1P2RY6P2RY14 | |
| Phosphoric Acid SCHEMBL23748501 | 0.97 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL6524192 | 0.95 | POLB (0.70) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL9706035 | 0.94 | POLB (0.68) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14429249 | 0.93 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14568629 | 0.93 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14568644 | 0.93 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14429239 | 0.93 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005706-A | Preparation method of 2',3' -dideoxynucleotide | 天津奥利芙生物技术有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-113151261-A | Antisense oligonucleotides as inhibitors of TGF-R signaling | 神经视觉医药有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107002082-B | Antisense oligonucleotides as inhibitors of TGF-R signaling | 神经视觉医药有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-20200069717-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-03-05 | — | — | US | disclosed |
| EP-2294076-B1 | CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED REPLICATION OF NUCLEIC ACID | TRILINK BIOTECHNOLOGIES (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20130053258-A1 | COMBINATORIAL LIBRARY, A METHOD FOR PREPARATION OF THAT COMBINATORIAL LIBRARY, A METHOD FOR SEQUENCE IDENTIFICATION, A METHOD FOR SEQUENCING THE ELEMENTS OF COMBINATORIAL LIBRARIES OF OLIGONUCLEOTIDES AND/OR OLIGONUCLEOTIDE ANALOGUES, THE USE OF A LINKER TO GENERATE COMBINATORIAL LIBRARIES AND A SEQUENCE IDENTIFICATION SET | INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) | 2013-02-28 | — | — | US | disclosed |
| US-20130053258-A1 | COMBINATORIAL LIBRARY, A METHOD FOR PREPARATION OF THAT COMBINATORIAL LIBRARY, A METHOD FOR SEQUENCE IDENTIFICATION, A METHOD FOR SEQUENCING THE ELEMENTS OF COMBINATORIAL LIBRARIES OF OLIGONUCLEOTIDES AND/OR OLIGONUCLEOTIDE ANALOGUES, THE USE OF A LINKER TO GENERATE COMBINATORIAL LIBRARIES AND A SEQUENCE IDENTIFICATION SET | INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) | 2013-02-28 | — | — | US | disclosed |
| EP-2550368-A1 | A COMBINATORIAL LIBRARY, A METHOD FOR PREPARATION OF THAT COMBINATORIAL LIBRARY, A METHOD FOR SEQUENCE IDENTIFICATION, A METHOD FOR SEQUENCING THE ELEMENTS OF COMBINATORIAL LIBRARIES OF OLIGONUCLEOTIDES AND/OR OLIGONUCLEOTIDE ANALOGUES, THE USE OF A LINKER TO GENERATE COMBINATORIAL LIBRARIES AND A SEQUENCE IDENTIFICATION SET | Instytut Chemii Bioorganicznej PAN (PL) | 2013-01-30 | — | — | EP | disclosed |
| US-8133669-B2 | Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid | TRILINK BIOTECHNOLOGIES (US) | 2012-03-13 | — | — | US | disclosed |
| WO-2011119057-A1 | A COMBINATORIAL LIBRARY, A METHOD FOR PREPARATION OF THAT COMBINATORIAL LIBRARY, A METHOD FOR SEQUENCE IDENTIFICATION, A METHOD FOR SEQUENCING THE ELEMENTS OF COMBINATORIAL LIBRARIES OF OLIGONUCLEOTIDES AND/OR OLIGONUCLEOTIDE ANALOGUES, THE USE OF A LINKER TO GENERATE COMBINATORIAL LIBRARIES AND A SEQUENCE IDENTIFICATION SET | INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) | 2011-09-29 | — | — | WO | disclosed |
| EP-0570514-A1 | METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM | GILEAD SCIENCES, INC. (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5217866-A | Polynucleotide assay reagent and method | ANTI-GENE DEVELOPMENT GROUP (US) | 1993-06-08 | — | — | US | disclosed |
| US-5142047-A | Morpholino nucleosides for blocking targeted genetic sequence | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0216860-A4 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0215942-A4 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1988-08-23 | — | — | EP | disclosed |
| EP-0216860-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0215942-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005518-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |
| WO-1986005519-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |
| EP-0090789-A1 | Chemical DNA synthesis | MONSANTO COMPANY (US) | 1983-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069717-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | POLRMT, NSUN2, RNGTT | POLB 12/4885ABL1 565/4885RIN1 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.